Haplotype exclusion by gene fusion errors based on the Mouse system

Hapex is here

The principle: The program Hapex, for haplotype exclusion,uses a cellular automaton approach to calculate the gene rearrangement events in a large sample of cells. The less likely a gene rearrangement pattern, the more cells have to be looked at. At a rough estimate there is little of likely interest when cell numbers exceed one million.

The parameters:

The idea is to pick your favorite model and generate the rearrangement patterns that result, then see if the patterns fit your data.

If your model is not accommodated or you have results that seem to be unsimulatable with the options provided, please let us know so that we can adjust the program to simulate your model or the data. Eventually we hope that only one model will simulate all of the data.

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